People
RSZ TNC Faculty
Jed Hubbs, PhD
Faculty, Harvard Medical School; Director, Medicinal Chemistry, Rosamund Stone Zander Translational Neuroscience Center at Boston Children’s Hospital
Dr. Hubbs is seeking to discover new drugs for neurological disorders and is particularly focused on genetically defined neurodevelopmental disorders and their effect on patients throughout their lifespans. His approach uses both target-based screening and drug optimization and phenotypic-based approaches. For the latter, he leverages the recent availability and standardization of patient iPSC-derived neurons and seeks to understand the underlying biology of molecules that correct disease-related phenotypes.
Dr. Hubbs is Assistant Professor of Neurology at Harvard Medical School and a faculty member at the Rosamund Stone Zander Translational Neuroscience Center at Boston Children’s Hospital. He was trained in synthetic organic chemistry and received his PhD in chemistry from the University of California, Berkeley under the supervision of Clayton Heathcock and completed an NIH Postdoctoral Fellowship with David Evans at Harvard University. He developed his skills as a medicinal chemist with more than 15 years of experience in the pharmaceutical industry and biotech. Most recently, he cofounded and served as CEO at Neurocycle Therapeutics where he led a team that brought a subtype selective GABAA receptor modulator into clinical trials before selling the company.